ACS GCI Pharmaceutical Roundtable—Catalyzing green chemistry & engineering in the global pharmaceutical industry.

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2020

Green Chemistry Articles of Interest to the Pharmaceutical Industry; Marie-Gabrielle Braun, Oliver Engl, Kenneth Fraunhoffer, John Hayler, Matthew Hickey, Jonathan Latham, Lucie E. Lovelle, Mark McLaws, Paul Richardson, Philipp C. Roosen, Alan Steven, Jack A. Terrett, Timothy White, Jingjun Yin. Org. Process Res. Dev. 2020, 24, 6, 897–908. DOI: 10.1021/acs.oprd.0c00154

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2019

A Green Chemistry Continuum for a Robust and Sustainable Active Pharmaceutical Ingredient Supply Chain; Stefan G. Koenig, Cisco Bee, Alina Borovika, Christiana Briddell, Juan Colberg, Guy R. Humphrey, Michael E. Kopach, Isamir Martinez, Sudhir Nambiar, Scott V. Plummer, Seth D. Ribe, Frank Roschangar, Jeremy P. Scott, Helen F. Sneddon. ACS Sustainable Chem. Eng. 2019, 7, 16937−16951. DOI: 10.1021/acssuschemeng.9b02842

Bringing Macrolactamization Full Circle: Self-Cleaving Head-to-Tail Macrocyclization of Unprotected Peptides via Mild N-Acyl Urea Activation; Christine A. Arbour, Kayla J. Belavek, Rooha Tariq, Subha Mukherjee, Janine K. Tom, Albert Isidro-Llobet, Michael E. Kopach, Jennifer L. Stockdill. J. Org. Chem. 2019, 84(2), 1035-1041. DOI: 10.1021/acs.joc.8b02418

Green Chemistry Articles of Interest to the Pharmaceutical Industry, Issue 23; Marie-Gabrielle Braun, John Hayler, Andrew Parsons, Alba Díaz-Rodríguez, Matthew Hickey, Paul Richardson, Louis Diorazio, Lucie Lovelle, Doru Roiban, Kenneth Fraunhoffer, Mark McLaws, Alan Steven. Org. Process Res. Dev. 2019, 23, 6, 1118-1133. DOI: 10.1021/acs.oprd.9b00158

Green Chemistry Articles of Interest to the Pharmaceutical Industry, Issue 24; Marie-Gabrielle Braun,  John Hayler, Andrew Parsons, Alan Steven, Jonathan Latham, Matthew Hickey, Paul Richardson, Jack A. Terrett, Louis Diorazio, Lucie Lovelle, Doru Roiban, Timothy White, Kenneth Fraunhoffer, Mark McLaws, Philipp C. Roosen, Jingjun Yin. Org. Process Res. Dev. 2019, 23, 2287-2301. DOI: 10.1021/acs.oprd.9b00450

Introduction of a process mass intensity metric for biologics; Kristi Budzinski, Megan Blewis, Philip Dahlin, Daniel D’Aquila, Julia Esparza, Jack Gavin, Sa V. Ho, Clarice Hutchens, David Kahn, Stefan G. Koenig, Robert Kottmeier, Jeff Millard, Matt Snyder, Brad Stanard, Lixin Sun.
New Biotechnology. 2019, 49, 37-42. DOI: 10.1016/j.nbt.2018.07.005.

Making the move towards modernized greener separations: introduction of the analytical method greenness score (AMGS) calculator; Michael B. Hicks, William Farrell, Christine Aurigemma, Laurent Lehmann, Lauren Weisel, Kelly Nadeau, Heewon Lee, Carol Moraff, Mengling Wong, Yun Huangh, Paul Ferguson. Green Chem., 2019 ,21, 1816-1826. DOI: 10.1039/C8GC03875A

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production; Albert Isidro-Llobet, Martin N. Kenworthy, Subha Mukherjee, Michael E. Kopach, Katarzyna Wegner, Fabrice Gallou, Austin G. Smith, Frank Rrochangar. J. Org. Chem. 2019, 84(8), 4615-4628. DOI: 10.1021/acs.joc.8b03001

The PMI Predictor – a Web App Enabling Green-by-Design Chemical Synthesis; A. Borovika, J. Albrecht, J. Li, A. S. Wells, C. Briddell, B. R. Dillion, L. J. Diorazio, J. R. Gage, F. Gallou, S. G. Koenig, M. E. Kopach, D. K. Leahy, I. Martinez, M. Olbrich, J. L. Piper, F. Roschangar, E. Sherer, M. D. Eastgate. ChemRxiv, Preprint 1/16/2019

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2018

Green Chemistry Articles of Interest to the Pharmaceutical Industry; Org. Process Rev. Dev., 2018, 22, (12), 1699-1711, DOI:10.1021/acs.oprd.8b00363

Evaluating the Impact of a Decade of Funding from the Green Chemistry Institute Pharmaceutical Roundtable; Org. Process Rev. Dev., 2018, 22, (10), 1344-1359, DOI:10.1021/acs.oprd.8b00237

Green Chemistry Articles of Interest to the Pharmaceutical Industry; Org. Process Rev. Dev., 2018, 22, (612), 667-680, DOI:10.1021/acs.oprd.8b00056

Inspiring process innovation via an improved green manufacturing metric: iGAL; Green Chem., 2018, 10, 2206-2211, DOI:10.1039/C8GC00616D

Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited.
Marian C. Bryan, Peter J. Dunn, David Entwistle, Fabrice Gallou, Stefan G. Koenig, John D. Hayler, Matthew R. Hickey, Shaun Hughes, Michael E. Kopach, Gerard Moine, Paul Richardson, Frank Roachangar, Alan Steven, Frans J. Weiberth.
Green. Chem. 2018, 20, 5082-5103. DOI: 10.1039/C8GC01276H

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2007

Key Green Chemistry Research Areas: A Perspective from Pharmaceutical Manufacturers
David J. C. Constable, Peter J.Dunn, John D. Hayler, Guy R. Humphrey, Johnnie L Jr. Leazer, Russell J. Linderman, Kurt Lorenz, Julie Manley, Bruce A. Pearlman, Andrew Wells, Aleksey Zaksh, Tony Y. Zhangf. Green Chem. 20079, 411-420. DOI: 10.1039/B703488C

Key Green Chemistry Research Areas: A Perspective from Pharmaceutical Manufacturers

Lessons Learned Through Measuring Green Chemistry Performance

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2008

Collaboration to Deliver a Solvent Selection Guide to the Industry

Green Chemistry Articles of Interest to the Pharmaceutical Industry
Stephen Challenger, Leo Dudin, Jimmy DaSilva, Peter Dunn, Tom Govaerts, John Hayler, Bill Hinkley, Yannis Houpis, Thomas Hunter, Lisa Jellet, John L. LeazerJr., Kurt Lorenz, Suju Mathew, Thomas Rammeloo, Ravinder Sudini, Zonghui Wan, Chris Welch, Andrew Wells, Jennifer Vance, Chaoyu Xie, Fuyao Zhang. Org. Process Res. Dev. 200812 (5), 807–816. DOI: 10.1021/op800175p

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