The overwhelming majority of bulk active pharmaceutical ingredient manufacturing is accomplished through the use of traditional batch chemical unit operations. Roundtable members have recently organized around a shared desire to promote the development, implementation, and routine use of continuous flow technologies within the Pharmaceutical industry, and to quantify the benefits from a green perspective.
Drew Bogdan, Tony Didomenico (Abbvie), Eric Moschetta (Abbvie), Benjamin Rizkin (Abbvie), Thad Franczyk (Abbvie), Alina Borovika (BMS), Tim Braden (Lilly), Isamir Martinez, David Constable (ACS GCI), Hsiao-We Hsieh (Amgen), Wenli Liang (Biogen), Niall McCreanor (AZ)
Promote the use of Continuous Flow within the Pharma Industry, and quantify benefits from a green perspective. Share best practices. Encourage the uptake of continuous flow.
Updated: March 2021
- Completed RFP for grants on the topic of solvent use minimization in flow.
- Completed planning for flow chemistry-themed technical session at 2021 ACS GC&E on the topic of flow chemistry as a tool for sustainable chemical development and manufacturing.
- Met several times over previous year with Andrew Teixeira (Worcester Polytechnic Institute) regarding development for curriculum for his new hands-on training in flow chemistry developed with AIChE RAPID institute funding
- Due to shifting timelines related to COVID, Teixeira course may be pushed back, and further opportunities for consultation may exist
- Seeking combined meetings with process analytical technology (PAT) focus team representatives to find areas for collaboration.
- Promote flow session at the GCE meeting via NEXUS blog in March.
- Reach out to colleagues with good social media presence to assist in promoting RFP and GC&E session once RFP is published.