ACS GCI Pharmaceutical Roundtable—Catalyzing green chemistry & engineering in the global pharmaceutical industry.

REACH

The REACH sub-team ensures the strong connection between chemical legislation and green chemistry is recognized, understood and communicated transparently within our member companies. Chemical legislation usually impacts where there is concern for potential harm to human health or environmental detriment. REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) is the most notable and arguably the most proactive of the variety of chemical legislation that exists. For this reason, it is the team’s focal point (but not the alone) in the groups review and consideration of business impact.

There are a variety of activities associated with the REACH legislation that have the potential to significantly impact the Pharmaceutical industry including solvents, surfactants and bespoke reagents. The roundtable has organized around these issues to share best practices and provide industry perspective to legislators as appropriate.

Team Lead

 

Barry Dillon

Goal

Ensure the strong connection between chemical legislation and green chemistry is recognized, understood and communicated transparently within our member companies.

Team Folder

DMS: REACH

Projects

Review of alternatives to dipolar aprotics within small molecule synthesis.

Team Status

Updated: October 2018

Achievements

  • Kick-off meeting
  • Draft team
  • Agreement as an opportunity to bring together technical chemistry/synthesis knowledge and experience with legislative awareness
  • October 2018 meeting discussion of ‘new/untested’ dipolar aprotic solvents

Challenges

  • Don’t want to duplicate the efforts of the Chemical Legislation (ChemLeg) group. Its an active group with significant overlap of members
  • Balanced messages of awareness (not overstating concerns)
  • Short and succinct communications/interplay with main groups &/or subgroups

Activity Snapshot

  • Review of alternatives to dipolar aprotics within small molecule synthesis.
  • Awareness of ongoing ‘big ticket’ legislative impacts to pharma (Dipolar Aprotics, Triton X100, Chromium etc)
  • Increasing discussion for ownership of proactive solutions to dipolar aprotic solvent challenges

Upcoming Projects

  • Team members to take back balanced messages to internal departments concerning Green Chemistry with legislative backing.